São Paulo vs LDU Quito Prediction, Betting Tips, Lineups & Odds | 25 Sep 2025

Copa Libertadores Betting Preview: São Paulo vs LDU Quito

Brazilian Série A club São Paulo host Ecuadorian LigaPro team LDU Quito in the second leg of this Copa Libertadores quarter-final tie, with kick-off set for 06:00 on Friday 26 September. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats, team news and confirmed lineups.

Go For Under 2.5 Goals With Confidence

Our research tells us that odds of 1.70 about Under 2.5 Goals looks like a solid wager for the São Paulo v LDU Quito contest. This Total Goals market bet has a strong chance of landing a return.

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LDU Struck Twice to Defeat São Paulo in First Leg

São Paulo were defeated in their last game. Away from home, they suffered a 1-0 Série A loss against Santos. Hernan Crespo's men boasted 56% possession and had one shot on target.

LDU Quito were defeated in their previous game, losing 4-2 at home to Universidad Catolica in the LigaPro. Lautaro Pastran and Kevin Minda found the net for Los Albos at Estadio Rodrigo Paz Delgado.

Head-to-Head Statistics

LDU claimed a 2-0 home victory against São Paulo in the first leg. The visitors dominated possession with 59%, but it was the hosts who proved more clinical, edging the shots on target 5-4. Bryan Ramírez and Michael Estrada both found the net to give LDU a strong lead heading into the return leg.

LDU have landed victory in two of the previous 3 H2H games, with São Paulo winning once.

Copa Libertadores		G	W	D	L	GF	GA	GD	GD	P
1	LDU Quito	6	3	2	1	8	4	4	8:4	11
1	São Paulo	6	4	2	0	10	4	6	10:4	14

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São Paulo vs LDU Quito Prediction & Betting Tips

From our main match prediction to correct score advice, must-watch player props and a custom bet builder — this São Paulo vs LDU Quito betting preview covers it all.

Match Prediction

The two teams might not deliver too many goals and that leads us to bet Under 2.5. This Copa Libertadores selection could be the way forward and that’s especially considering you can get odds of 1.70.

It's essential to know the players who are missing for the next clash along with the form for each of the two sides. If you’re looking for the best Copa Libertadores stats, we will showcase them and they provide the foundation for our football picks.

Key São Paulo vs LDU Quito Copa Libertadores & league stats:

• The 2.5 line hasn’t been covered in the last 6 São Paulo games.
• The 2.5 line hasn’t been covered in 8 of the last 10 São Paulo games.
• The 2.5 line hasn’t been covered in 12 of the last 20 São Paulo games.
• The 2.5 line hasn’t been covered in the last 5 LDU games on the road.
• The 2.5 line hasn’t been covered in 8 of the last 10 LDU games.
• The 2.5 line hasn’t been covered in 13 of the last 20 LDU games on the road.

Under 2.5 Probability

The best football bookies are estimating that there is a 58.8% likelihood of this pick landing a return. However, our experts have this number between 65-70% based on their in-depth research. It’s the reason why we are recommending this bet.

For those in pursuit of a larger price, there’s an opportunity to have a wager on Under 1.5 Goals, with bettors requiring no more than one goal to be scored in order for the bet to land.

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Our Match Prediction

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Gamble responsibly 18+. All odds are correct at time of publishing and are subject to change. To use the Bookmaker Live Streaming services you will need to be logged in and have a funded account or to have placed a bet in the last 24 hours. Geo-restrictions apply.

Correct Score Prediction

São Paulo 2 - 0 LDU

São Paulo are available to back at 5.00 to secure a 2-0 victory. This is a risky but potentially more rewarding bet, with this correct score option providing appeal.

Player Prop Picks

São Paulo vs LDU Quito Odds

The odds are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

São Paulo Big Favourites With the Bookies

With an estimated 73% chance of winning, the bookies are taking few chances with their 1.37 betting odds about São Paulo triumphing in this Copa Libertadores clash. LDU Quito are the underdogs at 10.50 which implies a low percentage prospect of winning.

An Asian Handicap -1.25 bet on São Paulo gives you a full payout at 1.89 if they beat LDU by two or more goals. If they win by one, you get half your stake returned but will lose the other half.

If you’re anticipating that two goals or less will be netted throughout the contest, then Under 2.5 Goals is a definite runner. If you believe this suggests that there will be a one-sided or low-scoring affair, then BTTS No could be a great pick at 1.38.

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Luciano da Rocha is the First Goalscorer Favourite

Favourite Luciano da Rocha is 4.10 to be the First Goalscorer, while similar odds apply when it comes to him scoring the last goal.

Latest Copa Libertadores and domestic league stats. Full Time Result, Goals, Corners and Possession.

São Paulo Stats

LDU Quito Stats

Full-Time Result

• 7 wins, 2 defeats and 1 draw in the previous 10 matches
• 7 wins, 2 defeats and 1 draw in the previous 10 home matches

Full-Time Result

• 4 wins, 3 defeats and 3 draws in the previous 10 matches
• 5 wins, 4 defeats and 1 draw in the previous 10 away matches

Goals

• An average of 1.50 goals scored and 0.60 conceded in the previous 10 matches
• An average of 1.50 goals scored and 0.80 conceded in the previous 10 home matches
• An average of 2.10 goals per game in the previous 10 matches
• An average of 2.30 goals per game in the previous 10 home matches
• BTTS Yes in 3 of the previous 10 matches
• BTTS Yes in 4 of the previous 10 home matches
• Over 2.5 Goals in 3 of the previous 10 matches
• Over 2.5 Goals in 4 of the previous 10 home matches

Goals

• An average of 1.20 goals scored and 1.10 conceded in the previous 10 matches
• An average of 1.20 goals scored and 0.90 conceded in the previous 10 away matches
• An average of 2.30 goals per game in the previous 10 matches
• An average of 2.10 goals per game in the previous 10 away matches
• BTTS Yes in 5 of the previous 10 matches
• BTTS Yes in 4 of the previous 10 away matches
• Over 2.5 Goals in 3 of the previous 10 matches
• Over 2.5 Goals in 4 of the previous 10 away matches

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São Paulo vs LDU Quito Lineups & Team News

The São Paulo vs LDU team news could change everything — review it before betting. We’ll share both predicted and confirmed lineups for the Copa Libertadores along with the latest injury news.