USC vs Purdue Prediction, Picks & Odds | 13 Sep 2025

College Football Betting Preview: USC vs Purdue

USC face off against Purdue in this NCAAF matchup at Ross-Ade Stadium, with kickoff scheduled for 03:30 on Sunday 14 September. Our betting preview features expert predictions, picks, the latest betting odds and H2H stats.

We’re Expecting a Low Points Total

We’re not convinced Purdue and USC are cumulatively going to produce enough points in relation to the total line. Therefore, we’re aiming to go Under 58.5 at 1.91.

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Both Teams Victorious in Last Game

USC Trojans claimed a home victory in their previous game. A 59-20 triumph against Georgia Southern Eagles at LA Memorial Coliseum made it back-to-back wins.

Purdue Boilermakers made it back-to-back wins in their last game. Landing a 34-17 home victory against Southern Illinois at Ross-Ade Stadium.

Quarterbacks

Jayden Maiava

Ryan Browne

USC vs Purdue Prediction & Picks

Make the most of USC vs Purdue with our betting analysis that includes an expert match prediction, expected scoreline, key player prop picks and a value-focused bet builder.

Game Prediction

When the teams line up in this college football matchup, we’re not sure that the total points will go over the line. Based on this pick, you can land odds of 1.91 for Under 58.5 and this looks worth taking.

The CFB handicappers at jetwinbet.com always keep close tabs on team news as it develops. We also rely on recent form and key stats to help shape our picks and guide the final call.

Key USC vs Purdue stats:

• The 58.5 line hasn’t been covered in the last 6 USC games on the road.
• The 58.5 line hasn’t been covered in 11 of the last 20 USC games on the road.
• The 58.5 line hasn’t been covered in 4 of the last 5 Purdue games at home.
• The 58.5 line hasn’t been covered in 7 of the last 10 Purdue games.
• The 58.5 line hasn’t been covered in the last 2 Purdue games.

Under 58.5 Probability

According to the top sportsbooks, our pick has a 52.4% chance of delivering a return. In the opinion of our analysts, there’s actually a probability of success closer to 60%. This is why we regard this as a value bet.

Bigger odds are always a good thing and bettors can regularly move the line when it comes to wagering Under on the Totals. Choose the option which suits you best.

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Best Bet

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Player Prop Picks

Correct Score Prediction

USC 41 - 10 Purdue

Should you want to go for a selection at massive odds, head to the correct score lines where the Trojans can be backed speculatively to achieve a 41-10 victory.

USC vs Purdue Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

USC Heavy Favorites to Win

USC are massive 1.06 favorites. They are regarded as 94% likely to win this college game judging by the sportsbooks’ latest Moneyline odds. For those wanting to oppose the market leader, you can get 9.60 about Purdue.

The current spread is 21.5 and the total points line is 59.5. The beauty of the Totals is that you only have to choose from one of two options. Those that want to back Under 59.5 can find odds of 1.87 available.

When it comes to college football, the top betting apps deliver a wide variety of game lines and team props. With so many options available, it’s worth taking your time to find the wager that fits your view of the matchup.

Waymond Jordan Favorite to Score First TD

There is 1.36 available that Waymond Jordan scores a TD at any stage. He is available at 4.20 to register the first touchdown which makes him favorite.

Touchdown

Receiving Yards

Rushing Yards

Passing Yards

Micro Betting

It’s good to consider all wagering options when it comes to college football and micro betting can be an exciting way to get involved in the action. When everything goes in-game, consider whether a player will make or miss a field goal.

Purdue Standing on Five Wins From Last Ten Home Matches

Purdue own a 5-5 mark in their past 10 home games, scoring 24.50 points per contest and conceding 28.20.

USC have a 4-6 record in their last 10 games away from home, posting 28.10 points per contest while yielding 31.30.

Last 10 Games		W-L	P	PF	PA	O58.5	U58.5
Purdue Home Stats		5-5	52.70	24.50	28.20	4	6
USC Away Stats		4-6	59.40	28.10	31.30	4	6

• W-L = Wins-Losses
• P = Avg. Points
• PF = Avg. Points For
• PA = Avg. Points Against
• O58.5 = Games Over 58.5 Points
• U58.5 = Games Under 58.5 Points

Last 5 & H2H

Latest regular season and playoff games stats.

USC Stats

Purdue Boilermakers Stats

Moneyline

• 6 wins and 4 defeats in the last 10 games
• 4 wins and 6 defeats in the last 10 games on the road

Moneyline

• 2 wins and 8 defeats in the last 10 games
• 5 wins and 5 defeats in the last 10 home games

Point Spread

• -21.5 Betting Line: Have covered the spread in 3 of the last 10 games
• -21.5 Betting Line on the Road: Have not covered the spread in any of the last 10 games on the road

Point Spread

• +21.5 Betting Line: Have covered the spread in 5 of the last 10 games
• +21.5 Betting Line at Home: Have covered the spread in 7 of the last 10 home games

Total Points

• Game Totals: An average of 62.40 pts in the previous 10 games
• Game Totals on the Road: An average of 59.40 pts in the previous 10 games on the road
• Over 58.5: Covered in 6 of the previous 10 games
• Over 58.5 on the Road: Covered in 4 of the previous 10 games on the road
• Team Totals: Have scored an average of 37.00 pts and allowed 25.40 pts in the last 10 games
• Team Totals on the Road: Have scored an average of 28.10 pts and allowed 31.30 pts in the last 10 games on the road

Total Points

• Game Totals: An average of 53.10 pts in the previous 10 games
• Game Totals at Home: An average of 52.70 pts in the previous 10 home games
• Over 58.5: Covered in 3 of the previous 10 games
• Over 58.5 at Home: Covered in 4 of the previous 10 home games
• Team Totals: Have scored an average of 16.70 pts and allowed 36.40 pts in the last 10 games
• Team Totals at Home: Have scored an average of 24.50 pts and allowed 28.20 pts in the last 10 home games

NCAAF Standings Select Season 2025/20262024/20252023/20242022/20232021/20222020/20212019/2020

Big Ten	W	L	PF	PA	N. Pts	Home	Away	Strk
Indiana	4	0	219	33	186	4-0	0-0	4W
Maryland	4	0	130	43	87	3-0	1-0	4W
Ohio State	3	0	121	16	105	3-0	0-0	3W
Oregon	4	0	203	37	166	3-0	1-0	4W
Penn State	3	0	132	17	115	3-0	0-0	3W
USC	4	0	210	81	129	3-0	1-0	4W
Washington	3	0	167	55	112	2-0	1-0	3W
Rutgers	3	1	167	96	71	3-1	0-0	1L
Nebraska	3	1	174	54	120	2-1	1-0	1L
Michigan State	3	1	137	115	22	3-0	0-1	1L
Michigan	3	1	140	71	69	2-0	1-1	2W
Iowa	3	1	132	58	74	2-0	1-1	2W
Illinois	3	1	145	85	60	2-0	1-1	1L
Minnesota	2	1	103	37	66	2-0	0-1	1L
Purdue	2	2	112	106	6	2-1	0-1	2L
Wisconsin	2	2	83	75	8	2-1	0-1	2L
Northwestern	1	2	59	64	-5	1-1	0-1	1L
UCLA	0	3	43	108	-65	0-2	0-1	3L